Welcome to UserCom — Issue 3: The Autonomous Lab
Laboratories are undergoing a fundamental shift. Automation is no longer reserved for high-throughput or industrial environments; it is becoming the backbone of modern science. From robotic arms that manage repetitive tasks to algorithms that predict titration endpoints, the tools shaping tomorrow’s lab are already in place.
In this issue, we showcase that transformation. Explore how collaborative robots and autosamplers reduce variability and boost throughput, how EVA Karl Fischer titrators use predictive control algorithms for reproducible results, and how LabX™ software connects instruments into seamless, audit-ready workflows. You will also find insights on spectroscopic integration, Gemba-style lab walks, and real-world case studies spanning pharmaceutical, food & beverage, chemical, and environmental settings.
Together, these stories highlight a new mindset: automation doesn’t replace scientific expertise; it amplifies it, freeing researchers to focus on analysis and discovery. We hope this edition offers both inspiration and practical guidance for your journey toward the autonomous lab.
Warm regards,
Yvonne Appoldt
Beyond Automation: The Autonomous Lab
Explore how robotics, AI, and cobots are transforming labs into collaborative, autonomous environments that boost precision and efficiency.
PX Autosamplers: Raising the Bar for Lab Automation
Innovative rinse cycles, chemical resistance, and LabX™ integration make PX autosamplers a sustainable leap forward in density and refractive index analysis.
From Syringe to Automation: Reproducibility Unlocked
A fruit juice study shows automation cuts analysis time in half and improves reproducibility from 0.3% variation to within 0.01% Brix.
EVA Karl Fischer Titrators: Driving Precision and Efficiency Through Automation
With the Fast Forecasting Amperometric (FFA™) Algorithm, EVA titrators predict endpoints dynamically, delivering faster, reproducible water content results with seamless LabX™ integration.
Automation That Transforms Thermal Analysis
Excellence systems replace subjective visual checks with automated melting and dropping point detection, boosting reproducibility, compliance, and safety while reducing sample use and waste.
Smarter pH Testing for Microliter Samples
The InLab® Micro Pro-ISM sensor delivers reliable pH results from as little as 150 µL, making every microliter count in pharmaceutical and biopharma workflows.
Smarter Biopharma Purity Testing With Automated UV/Vis
Cobots and autosamplers standardize UV/Vis QC, shorten turnaround times, and strengthen compliance for complex biologics.
Enhancing Spectroscopic Workflows with LabX™
From balance-linked concentration checks to multiparameter QC, LabX™ connects UV/Vis with other instruments, eliminating manual steps and ensuring audit-ready compliance.
The Future of Wine Tasting Is Digital
Fraunhofer IIS combines photoacoustic spectroscopy, autosamplers, and AI to digitize aroma analysis, making wine tasting faster, objective, and reproducible.
Inside Ramseier’s Journey to Automated Quality Control
By uniting density, refractive index, titration, and autosampling, Ramseier Suisse AG cut 10 minutes per sample and transformed beverage QC into a repeatable, compliant workflow.
One Run, Many Results: The Power of Multiparameter Testing
Density, refractive index, pH, and conductivity, measured in a single automated run. Multiparameter systems cut labor time by up to 70% while ensuring full regulatory compliance.
When UV/Vis Meets Intelligent Automation
InMotion™ autosamplers pair modular racks with smart workflows to scale UV/Vis, reduce errors, conserve solvents, and free scientists for discovery.
Explore how robotics, AI, and predictive systems are reshaping laboratory research. Learn why cobots are redefining precision, efficiency, and scalability, ushering in an era where scientists and machines collaborate to accelerate discovery.
Meet EVA, the next generation of Karl Fischer Titrators. Combining Swiss precision with the FFA™ Algorithm and smart automation, EVA delivers unmatched speed, reproducibility, and compliance, empowering labs to streamline workflows and safeguard data integrity.
Discover how PX Autosamplers transform density and refractive index analysis. Innovative rinse cycles cut solvent use, robust engineering ensures chemical resistance, and seamless LabX™ integration secures compliance, helping labs reduce costs while scaling throughput with ease.
See a fruit juice study shows why automation wins. Using the D5 Density Meter with InMotion™ PX One, labs achieved reproducibility within 0.01% Brix, versus 0.3% variation manually, while cutting analysis time by more than half.
Discover how Excellence instruments replace subjective visual checks with automated detection. Gain reproducible results, higher throughput, and full compliance, all while improving safety and sustainability with smaller sample volumes and smarter data handling through LabX™.
Measuring pH in tiny volumes has long challenged laboratories. With its slim design, built-in temperature probe, and automation-ready features, the InLab® Micro Pro-ISM delivers reproducible results, making every microliter count in pharmaceutical and biopharma workflows.
Laboratories face rising sample volumes, tighter timelines, and stricter regulations. InMotion™ autosamplers provide a way forward—pairing flexible rack systems with smart software to reduce errors, conserve solvents, and give scientists more time for discovery.
From sommeliers to spectrometers, wine evaluation is entering a new era. With PAS, automation, and AI, Fraunhofer IIS shows how aroma analysis can become faster, objective, and scalable, reshaping winemaking and inspiring applications across food science.
From legacy workflows to fully integrated automation, RAMSEIER Suisse AG modernized beverage QC with METTLER TOLEDO. Discover how automated degassing and multiparameter analysis reshaped throughput, reduced technician workload, and set a new benchmark for reliable, compliant beverage testing.
High-volume labs face rising pressure for speed and accuracy. By consolidating density, refractive index, pH, and conductivity into a single automated workflow, METTLER TOLEDO’s multiparameter systems cut labor time by up to 70% while ensuring robust compliance.
As biologics grow more complex, QC must keep pace. Automation with cobots and autosamplers turns UV/Vis into a standardized, reproducible process,shortening turnaround times, strengthening data integrity, and freeing scientists to focus on higher-value discovery.
From balance-linked concentration checks to multiparameter sugar color analysis and electrolyte QC, this article shows how LabX™ turns UV/Vis into the center of a connected workflow. Expect fewer errors, faster decisions, and compliance built in, across every spectroscopic application.
Yvonne Appoldt heads Analytical Chemistry at METTLER TOLEDO, where she spearheads strategic innovation and guides the unit’s direction.
Yvonne holds a PhD in Natural Sciences, a Master’s in Biochemistry, and a Master's in Business Administration, equipping her with a unique blend of scientific expertise and business acumen. This combination enables her to drive significant advancements in analytical chemistry, directly contributing to the enhancement of laboratory capabilities on a global scale.
