High Throughput Powder Dispensing

High throughput powder dispensing can increase productivity in pharmaceutical R&D workflows, such as screening and solubility testing. The pressure to reduce costs and increase efficiency of drug development has fostered the growth of high throughput experimentation (HTE), which is made possible by innovations in laboratory automation.

This poster describes a benchmarking study of automated powder dispensing systems, conducted by the Enabling Technologies Consortium (ETC), which compared several commercially available automated powder dispensing technologies. Quantos from METTLER TOLEDO proved to be accurate and reliable for dispensing small quantities of a wide range of powder types, commonly found in the laboratory. The latest innovation in this product family is the CHRONECT Quantos – a fully automated platform incorporating the trusted Quantos powder dispensing technology – enabling automated dispensing of 32 different powders into plate formats.

Find out more about the capabilities of automated powder dispensing.

HTE automation enables researchers to optimize route scouting and chemical development of new drug candidates, as well as to carry out solubility and stability screening more efficiently. One of the major bottlenecks encountered in HTE workflows is the time and effort necessary to manually weigh and prepare all of the samples and reaction materials required. Dosing a defined amount of powder is an increasingly important task in pharmaceutical R&D. Consequently, accurate automated weighing of small quantities of powders could have a huge impact on the efficiency of HTE workflows. Improvements in available technologies would benefit drug development by enabling more rapid screening, resulting in reduced lead time for new treatments and, ultimately, benefit patients and consumers.