Register now to download this essential guide detailing the integration of real-time reaction analysis into a robust process analytical technology (PAT) strategy.
For chemists and engineers focused on process development, scale-up, and Quality by Design (QbD), achieving maximum yield, purity, and sustainability requires generating and acting upon dense, high-quality data.
In this comprehensive guide, you will gain insights into:
Composition Monitoring Technologies: An objective review of the advantages of in-situ techniques, including FTIR, Raman, UV/Vis, NIR, NMR, and MS, for real-time data acquisition.
Advanced Separation Methods: Understanding the role and application of state-of-the-art chromatographic methods, such as UPLC, for online reaction analysis.
Targeted Applications Across Synthetic Disciplines: Strategies for applying these technologies to optimize and control processes in critical areas:
Organic Synthesis and Catalysis
Polymerization Kinetics
Crystallization and Particle Engineering
Biological Processes and Fermentation Monitoring
Sustainable and Continuous Flow Chemistry
Comprehensive Reaction Understanding
Insight into chemical reactions arises from a comprehensive understanding of reaction kinetics, mechanism and the effect of reaction variables on yields and impurity profiles. The need for safer and readily scalable reactions drive changes in how syntheses are performed, as an example, increased adoption of continuous flow methods. The analytical tools available to achieve reaction insight must also advance, driven by the demands to support more complex chemistry and new synthesis protocols.
