PAS-X MES Integration in Pharmaceutical Manufacturing

Discover How Advanced Weighing Equipment Improves Connectivity, Safety, and Quality

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22 Aug, 2025

Allie Myers

In pharmaceutical manufacturing, precise weighing and dispensing are crucial for product quality, patient safety, and regulatory compliance. PAS-X Weighing & Dispensing simplifies these steps with intelligent operator guidance, traceable workflows, and error-proof execution. We are proud to partner with Körber, a global MES leader, to facilitate smooth scale integration and smart weighing processes that fit modern manufacturing environments.

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A large pharmaceutical production facility faced the challenge of modernizing standalone weighing stations located in hazardous (Ex) areas. These stations often relied on legacy equipment with no digital interfaces, hence limiting traceability, increasing the risk of manual errors, and creating gaps in data integrity.

To meet compliance requirements across the entire process—including in ATEX-rated zones—intrinsically safe equipment that could connect directly with an MES was needed. Easy integration in these environments was critical not only for compliance but also for ensuring consistent data capture and workflow transparency throughout all production zones. Julia, the safety manager of the company, explains:

In order to remain compliant now and in the future, we need standardized, safe, and connected solutions throughout our facility.
Safety Manager CS

Seamless Integration in Hazardous-Area Weighing Solutions

Because our solutions integrate seamlessly with hazardous-area weighing requirements, safety and compliance are maintained effortlessly. Advanced METTLER TOLEDO indicators provide real-time analytics, helping reduce accident risks and promote a safer work environment. Additionally, being a certified partner within the Körber Ecosystem allowed us to help the facility integrate METTLER TOLEDO weighing equipment with their PAS-X MES. Remote access to weighing data facilitates quicker decision-making and supports smooth, efficient operations.

1. Hazarous-area weighing

2. PAS-X MES integration

3. Real-time analytics

4. Efficiency

Connected and Compliant Processes – Safety in Hazardous Areas

Download your copy of the story and discover how integrating intrinsically safe weighing solutions in hazardous areas can enhance compliance, safety, and operational efficiency.

In addition to compliance with ATEX regulation, the company aimed to unify formulation, dosing, quality, and filling processes within a single integrated system to improve traceability and sustain audit preparedness. When operating under stringent GxP regulations, ensuring equipment qualification, safeguarding data integrity, and maintaining real-time audit readiness are critical priorities. Maria, a product engineer, explains:

We required several solutions that connected seamlessly to our Manufacturing Execution System, Körber’s PAS-X-MES, while also improving legacy processes.
Maria, Production Engineer

Solution: PAS-X MES Connectivity

Being a certified partner within the Körber Ecosystem allowed us to help the facility integrate METTLER TOLEDO weighing equipment with their PAS-X MES in an effortless way that meets strict regulatory requirements, including 21 CFR Part 11 and EU Annex 11.

1. Hygienic weighing solution

2. PAS-X MES integration

3. Enhanced connectivity

4. Consistent quality

Solution: Good Weighing Practice

Throughout our consultation, we provided science-based recommendations for the right weighing equipment, ensuring the process needs were fully met by applying Good Weighing Practice™ (GWP®). We upgraded the systems with smart indicators that offer on-screen guidance for operators, improving quality control. On top of that, our hygienic weighing platforms designed for fast clean-in-place helped enhance safety and reduce cleaning time. Together, these modifications delivered enhanced connectivity, consistent quality, and increased safety across the GxP-critical applications.

From Manual Processes to Digital Precision

	Before Integration	After Integration
Data Entry	Manual, error-prone	Automated, validated
Operator Guidance	Paper-based SOPs	On-screen, interactive
Batch Documentation	Scattered and semi-digital	Centralized, EBR-ready
Cleaning Process	Manual wipe-down, complex	Open-frame, hygienic design

Consistent Process Connectivity – Precision in Pharma Production

Download your copy of the story to learn how this manufacturer streamlined operations, ensured data integrity, and met rigorous GxP and regulatory requirements, reinforcing their compliance posture and market leadership.

Moving Forward Together

By combining our precision weighing expertise with Körber’s advanced MES technology, we’re empowering pharmaceutical manufacturers to streamline operations, enhance compliance, and drive quality like never before. Regulatory demands evolve and production processes become continuously more complex. This partnership delivers innovative solutions that keep pharmaceutical manufacturing efficient, audit-ready, and aligned with ever-changing GxP and data integrity standards, every step of the way.

METTLER TOLEDO and Körber Partnership: Built on Trust, Shaped by Shared Customer Success

With a partnership history spanning over 20 years and many shared customers, joining the Körber Ecosystem partner program was a natural next step for us. This certified collaboration simplifies the use of PAS-X MES together with the METTLER TOLEDO industrial weighing sensor portfolio, providing the ideal weighing solution at every stage. From incoming goods, through manufacturing to delivery, all while supporting full GxP compliance.

Our collaboration extends beyond traditional weighing, enabling integration of METTLER TOLEDO scales into other critical process steps, e.g., Electronic Batch Recording (EBR), further supporting data integrity and audit readiness.