Enhancing Spectroscopic Workflows with LabX Integration

Automation, Compliance, and Efficiency Across UV/Vis Applications

Unifying Titration, Refractometry, Balances and UV/Vis with LabX Workflow

Spectroscopy sits at the heart of modern laboratories, from quality control in pharma to advanced materials research. Yet traditional workflows often rely on manual data transfers, calculations, and reporting, leaving room for errors, inefficiencies, and compliance risks.

By connecting UV/Vis spectrophotometers with other METTLER TOLEDO instruments through LabX software, laboratories can unlock seamless, end-to-end workflows. The result is data integrity, regulatory confidence, and significant time savings, all within a single connected ecosystem.

Figure 1. Step into the future of laboratory automation with LabX. The intuitive software platform seamlessly integrates your instruments and workflows to deliver precise data capture, automated analyses, and uncompromising data integrity.

Many spectroscopic workflows involve repetitive steps: recording data from balances, titrators, or refractometers, copying values into spreadsheets, and calculating results by hand. These manual processes not only consume valuable analyst time but also introduce transcription errors and compliance gaps.

With regulatory frameworks like 21 CFR Part 11 and ALCOA++ increasingly scrutinizing electronic data handling, laboratories need automated, auditable workflows that guarantee accuracy while reducing administrative burdens.

LabX brings automation, guidance, and secure data management to spectroscopy workflows by connecting UV/Vis systems directly with complementary instruments. Three typical integrations demonstrate the impact:

Figure 2. LabX workflow integrating a balance and UV/Vis spectrophotometer for automatic dissolution value transfer and automated

result calculation.

By linking balances directly with UV/Vis spectrophotometers through LabX:

Data integrity guaranteed: Weighing and absorbance values are automatically logged together in a secure audit trail.
Automated dissolution calculations: Real-time computation eliminates spreadsheets and calculator errors.
Guided workflows: On-screen prompts ensure every analyst follows the same validated process.

Benefit: Improved compliance, fewer mistakes, and reduced analyst workload.

2. Refractometer + UV/Vis Multiparameter Workflow

Combining refractive index with UV/Vis absorbance in a LabX-managed sequence enables:

Seamless data handover: Measurement results flow automatically between instruments, eliminating copy-paste steps.
Centralized reporting: All results stored in a single database for tailored reports on demand.
Operator guidance: Interactive prompts support reproducibility, even for inexperienced users.

Benefit: Higher throughput, simplified reporting, and complete traceability.

Figure 3. Schematic of R5 and UV5 multiparameter LabX workflow set-up.

Refractometer + UV/Vis Multiparameter Workflow

3. Titrator + UV/Vis Automated Process

In-line titration combined with spectroscopic detection delivers:

Automated workflow: Titration data flows directly into UV/Vis and LabX, removing manual entry.
Integrated calculations & archiving: Titration curves and absorbance data are processed and stored together.
Protocol enforcement: LabX enforces step-by-step checks to ensure best practices and compliance.

Benefit: Faster decision-making, shorter training times, and fewer deviations.

Figure 4. Schematic of multiparameter setup with titration and UV/Vis spectroscopy.

LabX integration transforms spectroscopic workflows from manual and fragmented into connected, automated, and compliant systems. By linking UV/Vis spectrophotometers with balances, refractometers, and titrators, laboratories save time, ensure reproducibility, and meet regulatory demands with confidence.

Hundreds of customizable application methods are available, from dissolution testing to multiparameter quality control, all designed to free analysts for higher-value tasks.

Ready to revolutionize your spectroscopy workflows? Download the free UV/Vis application notes and explore how LabX can unlock seamless integration across your METTLER TOLEDO instruments.

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Download the application package now to get instant access to the PDF application notes and all data files required for your LabX® software method - or download the single application notes below.

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App Note #1: Automated Multiparameter (Sugar) Analysis

Automating sugar analysis with LabX integrates refractometry, UV/Vis spectroscopy, balances, and pH meters into one ICUMSA®-compliant workflow. This seamless approach eliminates manual steps, accelerates throughput, and ensures precise, traceable results across food, beverage, and chemical applications.

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Download the Method File

Streamlined UV/Vis Spectroscopy and Refractometry LabX® Workflow for Sugar Color Analysis

App Note #2: Automated Concentration Analysis

This application note shows how LabX® integrates balances with UV/Vis spectrophotometers to automate concentration determinations. By eliminating manual input and recalculations, it ensures accuracy, traceability, and efficiency, providing laboratories with reliable, audit-ready data across routine analytical workflows.

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Download the Method Files

Automated Workflow for Reliable Concentration Determination by Integrating UV/Vis Spectroscopy and Balance with LabX

App Note #3: Automated Multiparameter Analysis (of Battery Electrolytes)

This application note shows how LabX unites titration and UV/Vis spectroscopy in a single workflow for battery electrolyte analysis. The integrated process accelerates QC, strengthens safety, and ensures compliance with complete traceability, guided protocols, and secure audit-ready data.

Download the Application Note

Download the Method Files

LabX-Driven Automated Testing for Battery Electrolyte Analysis by Titration and UV/Vis Spectroscopy

Anika Adams

Anika Adams is Product Manager for UV/Vis Spectrophotometers at METTLER TOLEDO, where she focuses on driving innovation and optimizing customer workflows.

With a degree in business administration and experience spanning software development, mechanical engineering, and production, Anika brings a multidisciplinary perspective to the laboratory business. Her expertise lies in automating and enhancing customer processes, ensuring both product excellence and customer satisfaction.

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